经阴道彩色多普勒超声测定血流速度、阻力指数对卵巢癌新辅助化疗效果的评估价值

Value of Trans-vaginal Color Doppler Ultrasound in Measuring the Blood Flow Rate and Resistance Index in Evaluating the Oophoroma Neoadjuvant Chemotherapy Effect

目的探讨经阴道彩色多普勒超声测定血流速度、阻力指数对卵巢癌新辅助化疗效果的评估价值。方法方便选取2016年1月—2017年6月该院收治的63例新辅助化疗卵巢癌患者为研究对象。化疗前后,以阴式彩超测量原发灶体积、血流速度及阻力指数,评估化疗效果。观察经阴彩超评估新辅助化疗效果的敏感度、特异度及符合率。结果阴式彩超化疗后测定原发灶体积(240.57±93.64)cm3、Vmax(3.12±0.75)cm/s、RI(0.71±0.06),对化疗前比较差异有统计学意义(P<0.05)。阴式彩超评价化疗灵敏度92.73%,特异度87.50%,符合率92.06%。结论阴式彩超是评价卵巢癌新辅助化疗效果的有效手段,测定血流速度和阻力指数能够较好的根据血流变化掌握病灶对化疗的反应,对治疗方案的及时调整具有积极作用,值得推广使用。

Objective To study the value of trans-vaginal color Doppler ultrasound in measuring the blood flow rate and resistance index in evaluating the oophoroma neoadjuvant chemotherapy effect. Methods 63 cases of patients with neoadjuvant chemotherapy in our hospital from January 2016 to June 2017 were convenient selected and the chemotherapy effect was evaluated according to the measurement values of primary lesion volume, blood flow rate and resistance index before and after chemotherapy, and the sensitivity, specificity and coincidence rate were evaluated. Results After chemotherapy,the measurement value of primary lesion, Vmax and RI by the trans-vaginal color Doppler ultrasound were respectively(240.57±93.64)cm3,(3.12±0.75)cm/s and(0.71 ±0.06), and the differences were statistically significant(P <0.05), and the sensitivity,specificity and coincidence rate of chemotherapy evaluated by trans-vaginal color Doppler ultrasound were respectively92.73%, 87.50% and 92.06%. Conclusion The trans-vaginal color Doppler ultrasound is an effective means of evaluating the oophoroma neoadjuvant chemotherapy, and it has a positive effect on the timely adjustment of treatment plan, and it is worth promotion and application.