奥扎格雷钠联合桂哌齐特治疗动脉硬化性脑梗死的临床疗效及对患者血液流变学、血脂的影响

Effect of Ozagrel Sodium Combined with Cinepazide on Arteriosclerotic Cerebral Infarction and Its Effect on Hemorheology and Blood Lipid in Patients

目的探讨奥扎格雷钠联合桂哌齐特治疗动脉硬化性脑梗死的临床疗效及对患者血液流变学、血脂的影响。方法该次以随机数字将方便选取2015年1月—2017年3月于该院诊治的动脉硬化性脑梗死患者60例分组为两组。每组30例。结果观察组临床治疗总有效率96.7%高于对照组76.7%,患者治疗后血浆黏稠(1.64±0.32)m Pa·s、红细胞压积(38.29±2.71)%、纤维蛋白原(3.45±1.42)g/L、血沉(3.16±0.27)mm/h、TG(1.97±0.43)mmol/L、TC(3.22±1.73)mmol/L、HDL(1.45±0.48)mmol/L、LDL(2.31±0.08)mmol/L等指标改善程度均优于对照组,差异有统计学意义(P<0.05)。结论选择奥扎格雷钠+桂哌齐特治疗动脉硬化性脑梗死患者的效果显著,可充分改善患者血液流变学及血脂情况,值得临床上广泛应用。

Objective This paper tries to investigate the clinical effect of ozagrel sodium combined with cinepazide on cerebral arteriosclerosis and hemorheology and blood lipid. Methods 60 cases of patients with cerebral infarction in this hospital from January 2015 to March 2017 were convenient selected and randomly divided into two groups. Results The clinical treatment efficiency of the observation group was 96.7%, higher than the control group of 76.7% after treatment, plasma viscosity of（1.64±0.32）m Pa·s, hematocrit of（38.29±2.71）%, fibrinogen of（3.45±1.42）g/L, erythrocyte sedimentation rate of（3.16±0.27）mm/h, TG of（1.97±0.43）mmol/L,TC of（3.22±1.73）mmol/L, HDL of（1.45±0.48）mmol/L, LDL of（2.31±0.08）mmol/L, better than the control group, the difference was statistically significant（P0.05）. Conclusion The effect of ozagrel sodium combined with cinepazide for cerebral arteriosclerosis in patients is significant, which can improve blood rheology and blood lipid, and is worthy of clinical application.