摘要
目的探讨降钙素原联合CRP对感染性休克病情严重程度及疗效评估的价值。方法方便选取从2016年6月—2017年5月入住该院住院治疗的80例存在感染的危重患者,按其是否合并感染性休克,分为对照组(非感染性休克组)与观察组(感染性休克组),40例/组。两组患者在确诊后使用抗生素前均采血1次,在积极的临床干预治疗后,每间隔1 d(即治疗第1、3、5天)空腹采血,对降钙素原、CRP进行测定,对比两组患者上述各项指标水平。结果比较两组患者治疗期间在相同的各个时间点监测的PCT、CRP,观察组较对照组有显著增高,差异有统计学意义(P<0.05);使用抗生素前,观察组患者PCT、CRP较对照组高,其PCT在第1天处于最高水平,CRP在第3天处于最高水平,经积极治疗,其PCT逐渐下降,CRP在第5天亦有显著下降,差异有统计学意义(P<0.05);而对照组患者PCT、CRP无明显下降,差异无统计学意义(P>0.05)。结论对于因感染性产生休克的重症患者,对降钙素原联合CRP进行评估,可为患者临床诊断及治疗提供可靠的参考依据,也作为治疗方案的可靠指标。
Objective This paper tries to investigate the value and its therapeutic effect of procalcitonin combined with CRP in evaluating the severity of infectious shock. Methods 80 cases of critically ill patients with infection from June 2016 to May 2017 were convenient selected and divided into the routine group（non-septic shock） and the observation group（septic shock）, 40 cases/group. Two groups of patients in the diagnosis of antibiotics before the use of blood once, after active clinical intervention, every other day（ie. Treatment for the first day, 3 day and the 5 day） fasting blood, the calcitonin, CRP were measured, the above indicators of the level of two groups were compared. Results Compared with the control group, PCT and CRP were monitored at the same time during the treatment of the two groups. The difference was statistically significant（P〈0.05）. Using antibiotics, PCT and CRP was higher in the observation group than the control group, the PCT at the highest level in the first day, CRP in the third day at the highest level, the active treatment, the PCT decreased gradually, CRP had also dropped significantly in the fifth day, the difference was statistically significant（P〈0.05）; In the control group, PCT and CRP did not decrease significantly（P〉0.05）. Conclusion The evaluation of procalcitonin combined with CRP in critically ill patients with septic shock can provide a reliable reference for clinical diagnosis and a reliable indicator of treatment options.
出处
《中外医疗》
2017年第33期109-111,共3页
China & Foreign Medical Treatment
