HPV感染与液基细胞学联合检测宫颈病变的临床分析

Clinical Analysis of HPV Infection and Liquid-based Cytology in Detecting Cervical Lesions

目的分析HPV感染与液基细胞学(TCT)联合检测宫颈病变的临床价值。方法方便选取2014年10月—2016年10月于该院妇科经病理证实为宫颈病变的80例患者为研究对象,对患者行HPV感染检查、液基细胞学检查(TCT)以及阴道镜检查,对比HSIL、ASCUS的阳性率。结果 HPV感染、TCT以及阴道镜检查联合检查结果显示HSIL阳性率最高(70.59%),高于HPV感染与TCT检查的58.33%,二者差异有统计学意义(P<0.05);HPV感染、TCT与阴道镜活检检查结果显示ASCUS的阳性率为30.23%,高于TCT与阴道镜活检的18.60%,两者差异有统计学意义(P<0.05)。结论在宫颈病变临床检测中行HPV感染与TCT联合检测可有效提升诊断率,避免漏诊的发生。

Objective This paper tries to analyze clinical value of HPV infection and liquid based cytology（TCT） in detection of cervical lesions. Methods 80 cases of cervical disease patients from October 2014 to October 2016 in this hospital confirmed by gynecological pathology were convenient selected as the research objects, and the patients were implemented HPV infection examination, liquid based cytology（TCT） and colposcopy examination, and then the positive rate of HSIL,ASCUS were compared. Results The examination results showed that the highest positive rate of HSIL of HPV infection,TCT and colposcopy was 70.59%, higher than that of HPV infection and TCT examination of 58.33%, with significant difference（P〈0.05）; HPV infection, TCT and colposcopy biopsy results showed that the positive rate of ASCUS was 30.23%, higher than 18.60% of TCT and colposcopy biopsy. There was a significant difference between the two groups（P〈0.05）. Conclusion The combined detection of cervical lesions in clinical detection by HPV infection and LCT can effectively improve the diagnostic rate and avoid misdiagnosis.