脊柱外伤患者焦虑抑郁情绪与预后相关性研究

The Correlation Analysis between Anxiety,Depression and Prognosis of Spine Injury Patients

目的:探讨脊柱外伤患者焦虑抑郁情绪与其预后的相关性。方法:选择2015年1月至2016年12月我院救治的脊柱外伤患者120例,根据有无合并焦虑抑郁障碍分为观察组68例和对照组52例。对患者焦虑抑郁情况进行评价时,利用焦虑自评量表(SAS)评分及抑郁自评量表(SDS)评分;数字疼痛分级法(Numerical rating scale,NRS)用于评价脊柱外伤手术后患者的疼痛程度;世界卫生组织生存质量调查表(Chinese version of WHO quality of life questionnaire,WHOQOL-BREF)用于评估患者术后的生存质量。比较两组患者术后疼痛、并发症发生率、6个月再住院率、6个月死亡率和生存质量等预后指标的差异。Pearson相关性分析和Logistic回归分析用于评估患者的焦虑抑郁与预后的相关性。结果:观察组患者的SAS、SDS评分、术后的并发症发生率、6个月再住院率、6个月死亡率以及NRS评分均显著高于对照组(P<0.05),而WHOQOL-BREF中各领域得分与各项合计总分均更低,差异有统计学意义(P<0.05)。患者的焦虑抑郁程度与其预后指标呈现显著的负相关性(P<0.05),亦即患者焦虑抑郁程度越大,预后越差。结论:脊柱外伤患者的焦虑抑郁情绪与预后情况密切相关,通过缓解患者的焦虑抑郁情绪,对于进一步改善患者的预后至关重要。

Objective: To investigate the correlation between anxiety and depression in patients with spine trauma and their prognosis.Methods: A total of 120 cases of spinal trauma were selected from January 2015 to December 2016 in our hospital. There were 68 in the observation group cases and 52 in the control groups. When evaluating anxiety and depression in patients,we use SAS score( anxiety selfrating scale) and SDS score( depression self-rating scale). Numerical rating scale( NRS) was used to evaluate the degree of pain of patients after spinal trauma. The world health organization's quality of life questionnaire( WHOQOL-BREF) was used to assess the quality of life after surgery. The differences in the prognosis indexes of postoperative pain,complication rate,6 month rehospitalization rate,6 month mortality and survival quality were compared. Pearson correlation analysis and Logistic regression analysis were used to assess the correlation between anxiety depression and prognosis in patients. Results: Observation group of patients with SAS,SDS score,postoperative complications and 6 months hospitalization rates,6 months mortality and NRS scores were significantly higher than the control group patients( P < 0. 05),while WHOQOL BREF-scores in various fields with the total scores were significantly lower than control group( P <0. 05). The degree of anxiety and depression of the patients showed a significant negative correlation with their prognostic indicators( P <0. 05),the more the patient's anxiety and depression,the worse the prognosis. Conclusion: The anxiety and depression in patients with spine trauma are closely related to the prognosis,and it is important to improve the prognosis of patients by alleviating the anxiety and depression in patients.