益赛普治疗类风湿关节炎30例疗效研究

Effect of Etanercept in the Treatment of 30 cases of Patients with Rheumatoid Arthritis

目的:观察益赛普治疗类风湿关节炎的临床疗效。方法:选择2014年1月~2016年1月收治的类风湿关节炎患者60例,随机分为观察组和对照组,每组30例,对照组使用甲氨蝶呤治疗,观察组在此基础上使用益赛普治疗,2个月后对比两组疗效。结果:(1)观察组显效19例,有效8例,总有效率为90.0%;对照组显效9例,有效10例,总有效率为63.3%(P<0.05);(2)观察组在治疗第4、8周时的ACR各指标改善情况均明显好于对照组(P<0.05)。结论:益赛普治疗类风湿关节炎疗效显著,安全可靠,值得推广。

Objective:To study the effect of etanercept in the treatment of rheumatoid arthritis.Methods:60 cases of patients with rheumatoid arthritis from January 2014 to January 2016 were randomly divided into observation group and control group,with 30 cases in each group,the control group was treated with methotrexate,and the observation group was treated with etanercept based on the control group,then the efficacy of the two groups was compared after 2 months.Results:(1)In the observation group,19 cases were markedly effective,8 cases were effective,the total effective rate was 90.0%;In the control group,9 cases were markedly effective,10 cases were effective,the total effective rate was 63.3%(P<0.05).(2)The improvement of ACR in the observation group at fourth,eighth weeks were better than those in the control group(P<0.05).Conclusion:The efficacy of etanercept in the treatment of rheumatoid arthritis is significant,safe and reliable,which is worthy of promotion.