探讨NSE检测对于急性脑出血患者诊治的应用价值

Application Value of NSE Detection for Acute Intracerebral Hemorrhage

目的探究检测血清神经元特异性烯醇化酶(NSE)对于急性脑出血诊治的指导意义。方法选取2016年1—12月在我院诊治的500例急性脑出血病例作为观察组,再选择同期500例正常体检者作为对照组,回顾性分析两组病例的临床资料以及NSE检测结果。结果观察组NSE浓度水平较对照组高(P<0.01);随着出血量增多、神经功能缺损严重度增加,观察组NSE浓度水平也逐渐升高(P<0.01)。结论 NSE检测水平可以体现急性脑出血患者出血量以及神经功能受损情况,能够作为急性脑出血临床诊治和预后评估的重要参考指标。

Objective To explore the application value of NSE detection for acute intracerebral hemorrhage. Methods 500 cases with acute intracerebral hemorrhage from January to December 2016 were selected as observation group and another 500 healthy cases in the same period were selected as control group. The clinical data and NSE results in the two groups were compared. Results In observation group, the improvement of concentration level of NSE were higher than control group （P 〈 0.01）. With the increaseof haemorrhage estimates and severity of neurologic impairment, the concentration level of NSE were increased in observation group （P 〈 0.01）. Conclusion NSE detection, as an important reference index, can reflect blood loss and severity of neurologic impairment for acute intracerebral hemorrhage.