凝血功能在心脑血管疾病患者检验中的参考意义

Significance of coagulation tests for the patients with cardiovascular disease

目的探讨凝血功能对心脑血管疾病患者预后的判断。方法选取97例本院的心脑血管疾病患者作为实验者,另选取97例健康体检人员作为对照组。比较患者8个凝血功能指标及实验组患者不同病情归转情况。结果治疗前,实验者患者凝血酶原时间(PT)、凝血酶时间(TT)、纤维蛋白酶原(Fbg)、D-二聚体(D-D)、内皮素-1(ET-1)、纤溶酶原激活剂抑制物-1(PAI-1)、抗凝血酶Ⅲ(AT-Ⅲ)和血栓调节蛋白(TM)均高于对照组(P<0.05);治疗后各项凝血功能指标均下降(P<0.05);预后病残患者PT、TT、Fbg、D-D、ET-1、PAI-1、AT-Ⅲ和TM均高于良好归转患者(P<0.05)。结论凝血功能检测对心脑血管疾病的预后判断具有重要意义。

Objective To discuss the effect coagulation tests for the patients with cardiovascular disease. Methods A total of 97 patients with cardiovascular disease who accepted treatment in our hospital were selected as observation group and 97 health controls were as control group. The eight coagulation function indicators and prognosis were compared. Results Before treatment,the levels of PT,TT,Fbg,D-D,ET-1,PAI-1,AT-Ⅲ and TM of observation group were significantly higher than that in the control group( P < 0. 05),all the coagulation function indexes above were significantly lower after treatment( P < 0. 05). The PT,TT,Fbg,D-D,ET-1,PAI-1,AT-Ⅲ and TM levels of the patients with poor prognosis were significantly higher than those with good prognosis in observation group( P < 0. 05). Conclusion Coagulation tests is of great significance to control prognosis for the patients with cardiovascular disease.