β-受体阻滞剂结合常规药物治疗瓣膜性心脏病心力衰竭分析

Analysis of β-blocker combined with conventional drugs in the treatment of heart failure of valvular heart disease

目的观察β-受体阻滞剂结合常规药物治疗瓣膜性心脏病心力衰竭的临床疗效。方法选取我院瓣膜性心脏病心力衰竭患者(200例),随机分为对照组和观察组,对照组采用常规治疗,观察组在对照组的基础上实施β-受体阻滞剂治疗,每组各100例,比较两组患者心率、血压及心功能指标改善情况。结果观察组瓣膜性心脏病心衰患者心率与对照组比较,差异有统计学意义(P<0.05)。但收缩压及舒张压对照组比较,差异无统计学意义(P>0.05)。观察组患者心功能指标改善情况均优于对照组,差异有统计学意义(P<0.05)。结论将β-受体阻滞剂结合常规药物应用于瓣膜性心脏病心力衰竭的治疗中,不仅能够改善患者心率及血压指标,同时还能使其心功能指标得到改善,值得研究。

Objective To observe the clinical efficacy ofβ-blocker combined with conventional drugs in the treatment of heart failure of valvular heart disease. Methods Two hundred patients with heart failure of valvular heart disease in our hospital were selected and divided into two groups randomly by computer,the control group-routine treatment and the observation group-the treatment of beta blockers on the basis of the control group,100 cases in each group.The improvement of heart rate,blood pressure and cardiac function were compared between the two groups. Results The heart rate of the patients with heart failure of valvular heart disease in the observation group was significantly different from that of the control group （P 〈0.05）.However,there was no significant difference in systolic pressure and diastolic pressure between the observation group and the control group （P 〉0.05）.The improvement of cardiac function index in the observation group was better than that of the control group（P 〈0.05）. Conclusion The application of β-blocker combined with conventional drugs in the treatment of heart failure of valvular heart disease can not only improve the heart rate and blood pressure index of patients,but also improve the heart function index,which is worth studying.