妊娠期显性糖尿病和妊娠期糖尿病患者在妊娠晚期临床特征差异

Difference in clinical features of patients with dominant gestational diabetes mellitus and gestational diabetes mellitus in late pregnancy

目的探讨妊娠期显性糖尿病和妊娠期糖尿病患者在妊娠晚期临床特征差异。方法选取2016年4月~2017年5月我院诊治妊娠晚期妊娠期显性糖尿病患者100例(A组)和妊娠期糖尿病患者100例(B组)临床资料行回顾性分析,比较两组患者血糖水平、血压水平、营养状况及并发症发生情况。结果 A组患者Hb A1C、FPG、2h PG水平显著高于B组,差异有统计学意义(P<0.05)。A组患者SBP水平高于B组(P<0.05),两组患者DBP比较无统计学意义(P>0.05)。两组患者ALB、TP水平比较无统计学意义(P>0.05);A组患者HGB水平低于B组,差异有统计学意义(P<0.05)。A组患者肾功能损伤、子痫前期发生率显著高于B组,差异有统计学意义(P<0.05)。结论妊娠期晚期妊娠期显性糖尿病相对妊娠期糖尿病患者血糖水平更高、营养状况更差、并发症风险更高。

Objective To investigate that difference in clinical features of patients with dominant gestational diabetes mellitus and gestational diabetes mellitus in late pregnancy. Methods From April 2016 to May 2017,the clinical data of 100 cases （group A） of dominant gestational diabetes mellitus and 100 cases （group B） of gestational diabetes mellitus in our hospital were analyzed retrospectively.The blood glucose level,blood pressure level,nutritional status and complications in the two groups were compared. Results The levels of HbA1C,FPG and 2hPG in group A were significantly higher than those in group B （P 〈0.05）.The level of SBP in group A was higher than that in group B （P 〈0.05）.There was no significant difference in DBP between the two groups （P 〉0.05）.There was no significant difference in the level of ALB and TP in the two groups （P 〉0.05）.The level of HGB in group A was lower than that in group B （P 〈0.05）.The incidence of renal function injury and preeclampsia in group A was significantly higher than that in group B （P 〈0.05）. Conclusion In the late pregnancy,the patients with dominant gestational diabetes mellitus has a higher level of blood sugar,poorer nutritional status and a higher risk of complications than the patients with gestational diabetes mellitus.