应用三维斑点追踪技术评价肥厚型心肌病患者左室功能的价值

Evaluation of the value of left ventricular function in patients with hypertrophic cardiomyopathy by three-dimensional speckle tracking technique

目的应用实时三维斑点追踪定量技术评估肥厚型心肌病患者左室整体应变功能。方法选取36例肥厚型心肌病患者和25例正常对照组,通过三维斑点追踪技术测量左室心肌整体纵向、径向、圆周、及面积峰值应变值,进行比较分析。结果与对照组比较,肥厚型心肌病组左室心肌整体纵向应变、径向应变、面积应变、圆周应变等指标均减低,差异有统计学意义(P<0.05);GLS、GAS与左室舒张末期室间隔的最大厚度相关性良好(r=0.82、0.78,P<0.05);HCM组与对照组的LVEDV、LVESV、LVEF的传统心脏功能指标比较,差异无统计学意义(P>0.05)。结论 RT3D-STI评价肥厚型心肌病左室心肌功能准确、可行,为临床早期诊断提供了有价值的信息。

Objective To evaluate the overall left ventricular function in patients with hypertrophic cardiomyopathy by real-time three-dimensional speckle tracking quantitative technique. Methods Thirty-six patients with hypertrophic cardiomyopathy and 25 normal controls were selected.The total longitudinal,radial,circumference,and area peak strain of left ventricular myocardium were measured by three dimensional speckle tracking technique,and the comparative analysis was carried out. Results Compared with the control group,the overall longitudinal strain,radial strain,area strain and circumferential strain of left ventricular myocardium in hypertrophic cardiomyopathy group decreased,the difference was statistically significant （P 〈0.05）.The correlation between GLS,GAS and the maximum thickness of left ventricular septum was good （r=0.82,0.78, P 〈0.05）.There was no significant difference in the traditional cardiac function indices between the HCM group and the control group in LVEDV,LVESV and LVEF （P 〉0.05）. Conclusion RT3D-STI evaluation of left ventricular function in hypertrophic cardiomyopathy is accurate and feasible,which provides valuable information for early clinical diagnosis.