化瘀消癥汤联合西药在宫外孕保守治疗中的疗效及对患者血清CA125、β-HCG、孕酮水平的影响

Huayu Xiaozheng decoction combined with western medicine in the treatment of ectopic pregnancy and the influence in serum CA125、β-HCG、progesterone

目的:探讨化瘀消癥汤联合西药治疗宫外孕的疗效以及患者治疗前、后血清癌胚抗原125(CA125)、孕酮(P)、β-人绒毛膜促性腺激素(β-HCG)的变化情况。方法:选取78例宫外孕患者纳入本次研究,以随机法将全部患者均分为常规组与联合组,常规组采取常规西药治疗,联合组在同样执行常规组疗法的同时给予自拟化瘀消癓汤治疗,治疗2周后评估疗效并统计各项临床症状消失时间,观察治疗前、后两组患者P、CA125、β-HCG的变化情况。结果:常规组总有效率为66.67%,联合组总有效率为94.87%,联合组优于常规组(P<0.05);联合组主要症状恢复时间均少于常规组(P<0.05)。治疗2周后两组血清P、β-HCG、CA125水平均有所改善,组内对比P<0.05;同时联合组优于常规组,组间对比P<0.05。结论:化瘀消癓汤联合西药应用于宫外孕保守治疗中能够提高保守治疗成功率,改善血清CA125、P、β-HCG的表达水平。

Objective:To investigate the curative effect of Huayu Xiaozheng decoction combined with western medicine in the treatment of ectopic pregnancy and patients before and after treatment,serum carcinoembryonic antigen 125(CA125)and progesterone(P),human chorionic gonadotropin(beta-HCG)changes.Methods:78 cases of ectopic pregnancy were enrolled in this study,by random method,all patients were divided into routine group and combination group,conventional group received routine western medicine treatment,combined treatment group were treated with Huayu Xiaozheng decoction in the same group to perform routine blood stasis dredging therapy at the same time,after 2 weeks of treatment,evaluate the treatment effect and the clinical symptoms of statistics the time before and after treatment in two groups of P,CA125 and beta-HCG changes.Results:The conventional group total effective rate was 66.67%,the total efficiency of the combination group was 94.87%,the combined group was better than the conventional group(P<0.05 group);combined with main symptom recovery time were less than the normal group(P<0.05).After 2 weeks of treatment,serum P,beta-HCG and CA125 levels in the two groups were improved,compared with P<0.05 in the group;at the same time,the combined group was better than that of the conventional group,and the comparison between the two groups was P<0.05.Conclusion:Huayu Xiaozheng decoction combined with western medicine used in ectopic pregnancy conservative treatment can improve the success rate of conservative treatment,the expression level of P,improve the serum CA125 and beta-HCG.