药师参与抗凝治疗管理研究进展

Research Advances of Pharmacist-Participated Anticoagulation Therapy Management

抗凝管理对于安全、有效地进行长期抗凝治疗至关重要,临床药师参与抗凝治疗管理与医师或其他医疗人员相比,可提高患者的抗凝达标率,减少出血、血栓等不良事件的发生,提高患者依从性,降低医疗成本。目前抗凝治疗管理主要集中在华法林等维生素K拮抗剂上,管理多采用抗凝门诊形式,少数通过网络、电话等进行患者自我监测和管理,药师上门监测等模式。对于新型口服抗凝药的管理尚缺乏经验,仍待进一步的研究与摸索。了解药师参与管理抗凝治疗的进展,可为未来我国药师参与抗凝治疗管理的发展提供一定的依据。

Anticoagulation therapy management is vital for safe and effective long-term anticoagulation therapy. Compared with physicians and other health care givers,clinical-pharmacist-participated anticoagulation management can increase anticoagulation control rates and patient compliance and decrease adverse drug events,such as bleeding events and thrombosis events. Anticoagulation management is concentrated on warfarin and other vitamin K anticoagulants nowadays. Anticoagulation clinic is one of the most popular management models,self-monitoring and self-management by the internet and telephone and clinical pharmacist home visit are also adopted in some cased. New oral anticoagulants are wildly used recently,while the management experience is still insufficient needing further exploration. A through comprehension of advances of clinical-pharmacist-participated anticoagulation management worldwide,can provide references for the development of pharmacist-participated anticoagulation management in China in the future.