硬膜外麻醉复合全身麻醉用于直肠癌根治手术麻醉效果观察

Observation on anesthesia effect of epidural anesthesia combined with general anesthesia for radical resection of rectal cancer

目的研究硬膜外麻醉复合全身麻醉用于直肠癌根治手术麻醉的临床效果。方法 90例行直肠癌根治手术患者,采用随机数字法分为对照组和观察组,各45例。对照组采用全身麻醉,观察组在对照组基础上附加硬膜外麻醉,比较两组患者麻醉效果、生理指标以及不良反应发生情况。结果观察组麻醉优良率高于对照组,差异具有统计学意义(P<0.05);观察组麻醉0.5 h后平均动脉压、心率均优于对照组,差异具有统计学意义(P<0.05);观察组不良反应发生率为2.22%,对照组不良反应发生率为22.22%,观察组不良反应发生率明显低于对照组,差异具有统计学意义(P<0.05)。结论将硬膜外麻醉复合全身麻醉用于直肠癌根治手术中,麻醉效果显著,且能够有效改善患者生命体征,降低不良反应发生率,保证手术正常开展,值得临床推广。

Objective To study the clinical effect of epidural anesthesia combined with general anesthesia for radical resection of rectal cancer. Methods A total of 90 patients with radical resection of rectal cancer were divided by random number table method into control group and observation group, with 45 cases in each group. The control group received general anesthesia, and the observation group received epidural anesthesia on the basis of the control group. Comparison were made on anesthesia effect, physiological indicators and occurrence of adverse reactions between the two groups. Results The observation group had higher anesthesia excellent rate than the control group, and the difference was statistically significant （P〈0.05）. The observation group had better mean arterial pressure and heart rate after 0.5 h of anesthesia than the control group, and the difference was statistically significant （P〈0.05）. The observation group had incidence of adverse reactions as 2.22%, which was 22.22% in the control group. The observation group had obviously lower incidence of adverse reactions than the control group, and the difference was statistically significant （P〈0.05）. Conclusion Application of epidural anesthesia and general anesthesia in radical resection of rectal cancer shows remarkable anesthesia effect and can effectively improve vital signs, reduce incidence of adverse reactions and ensure normal development of operation. It is worthy of clinical promotion.