摘要
近年来,长链非编码RNA(lncRNA)备受关注。越来越多的研究表明lncRNA能通过不同的方式调节基因的表达,从而参与调控多种生物学进程,并与许多疾病的发生相关。对lncRNA的主要功能及其与个体发育、肿瘤发生相关的最新研究进展做简要综述。
Recently, long non-coding RNA(lncRNA) research has been paid attention increasingly. A growing number of researches suggest that lncRNA can regulate gene expression in different ways, involved in a variety of biological processes regulation and the occurrence of many diseases. In this paper, we reviewed the latest research progress of lncRNA on the main function and their roles on individual development and tumorigenesis.
出处
《生物技术通讯》
CAS
2018年第1期123-130,共8页
Letters in Biotechnology
基金
陕西省科技统筹创新工程计划(2014KTDZ02-01
2015KTTSNY04-03)
榆林学院高层次引进人才科研启动基金(16GK06)
关键词
长链非编码RNA
功能
个体发育
肿瘤
long non-coding RNA(lncRNA)
function
individual development
tumor