荧光碳点的制备及其肿瘤诊断和治疗中的应用研究进展

Progress in research on the preparation of carbon dots and their use in tumor theranostics

碳点是一种新型的碳基荧光纳米材料,因具有优异的荧光性能、低毒性、良好的水溶性及表面易修饰等优点,在生物医学领域有很好的应用潜力。本文重点从工艺的角度对碳点的制备进行阐述,介绍红光和近红外荧光碳点的研究进展,及碳点在诊断和治疗肿瘤方面的应用研究,探讨目前碳点发展的限制因素及未来的发展趋势。

Carbon dots （CDs）, as a novel class of carbon-based nanomaterials,have attracted tremendous attention in biomedi-cine owing to their excellent optical properties, low toxicity, good water solubility and easy surface modification. In this review, we introduce various methods for their synthesis based on technology and recent research progress on red-emission and near-infrared e-mission CDs, and address the use of CDs in the diagnosis and therapy treatment of tumors. The review also summarizes the limiting factors that affect the development of CDs and possible new advances.