摘要
目的了解遵义地区结核分枝杆菌耐药情况,并探讨其耐药特点,为耐药结核病的监测提供参考。方法采用比例法对我院门诊及住院的肺结核患者痰标本中分离到的74株结核分枝杆菌进行异烟肼、利福平、链霉素和乙胺丁醇4种一线抗结核药物的敏感性试验。结果 74例肺结核患者结核分枝杆菌对一线抗结核药的总耐药率为54.1%,耐多药率为12.2%。结论本地区结核分枝杆菌耐药情况严重,应进一步加强耐药结核的监测。
Objective To understand the drug resistance of mycobacterium tuberculosis in Zunyi and explore the char- acteristics of its drug resistance, so as to provide a reference for the surveillance of drug-resistant tuberculosis. Meth- ods 74 strains of mycobacterium tuberculosis isolated from sputum samples of outpatients and inpatients in our hospital were given sensitivity test of 4 kinds of first-line anti-TB drugs, including isoniazid, rifampicin, streptomycin and ethambutol. Results The total drug resistance rate of mycobacterium tuberculosis to first-line anti-tuberculosis drugs in 74 patients with pulmonary tuberculosis was 54.1%, and multi drug resistance rate was 12.2%. Conclusion The drug resistance of mycobacterium tuberculosis in this area is serious, and the surveillance of drug-resistant TB should be further strengthened.
出处
《中国现代医生》
2018年第1期130-132,共3页
China Modern Doctor
基金
贵州省科学技术基金项目(黔科合J字[2012]2354号)
关键词
结核分枝杆菌
药物敏感试验
耐药率
监测
Mycobacterium tuberculosis
Drug sensitivity test
Drug resistance rate
Surveillance
