低剂量化疗作用机制的研究进展

Research progress on mechanism of low-dose chemotherapy

化疗是肿瘤综合治疗的主要方式之一,多年来在肿瘤治疗中发挥着重要作用。但近年来低剂量化疗(Low-dose chemotherapy)利用其化疗药物的作用点,采取合理的给药方式和计划,且相对于最大耐受剂量化疗具有毒副反应小、患者耐受性明显提高、疗效更佳等优势,已逐渐成为临床中常用的治疗策略。本文就低剂量化疗的作用机制的研究进展做一系统综述。

Chemotherapy is one of the main ways for comprehensive treatment of tumors,and has played an important role in tumor treatment for many years. However,in recent years,low-dose chemotherapy（ Low-dose chemotherapy） has gradually become a clinical treatment strategy commonly used to taken a reasonable mode of administration and planning,relative to the maximum tolerated dose of chemotherapy with small side effects,patient tolerance significantly improved,better efficacy and other. In this paper,the mechanism of low-dose chemotherapy on the progress is reviewed systematicly.