食管支架的研究进展

Advance in research of esophageal stent

食管疾病是临床常见疾病,食管支架在食管疾病的治疗中有广泛的临床应用。但目前临床常用的食管支架存在诸多的置入后并发症问题,限制了食管支架的临床应用。生物可降解食管支架拥有可降解性和良好的组织相容性两大优势,它的出现有望解决目前食管支架存在的多种并发症问题,为食管疾病的治疗提供新的选择。应用3D打印技术制造生物可降解食管支架可以实现食管支架的个体化治疗,同时也能降低支架的制造成本。本文拟从食管支架的临床使用情况、生物可降解食管支架的研究进展和3D打印技术在可降解食管支架的应用前景作综述,以期为生物可降解食管支架领域中的研究提供依据和研究方向。

The esophageal disease is a major clinical disease. The esophageal stent has extensive clinical applications in the treatment of esophageal diseases. However, the clinical application of esophageal stent is limited, because there are lots of complications after implantation of esophageal stent. Biodegradable esophageal stent has two advantages： biodegradability and good histocompatibility. It is expected to solve a variety of complications of esophageal stent and provide a new choice for the treatment of esophageal diseases. Standardized esophageal stents are not fully applicable to all patients. The application of 3D printing technology in the manufacture of biodegradable esophageal stent can realize the individualized treatment of esophageal stent. And meanwhile, the 3D printing technology can reduce the manufacturing cost of the stent. This review aimed to summarize and discuss the application of esophageal stent, the current research status and prospect of biodegradable esophageal stent and the prospect of 3D printing technology in degradable esophageal stent, hoping to provide evidence and perspectives for the research of biodegradable esophageal stent.