不同方法皮下注射曲普瑞林对患儿舒适度的影响

Effects of different methods of subcutaneous injection of triptorelin on the comfort of children

目的探讨不同方法皮下注射曲普瑞林对患儿舒适度的影响。方法特发性中枢性早熟女性患儿94例需皮下注射曲普瑞林,随机分为观察组(n=48)和对照组(n=46)。对照组采用常规皮下注射法,观察组采用捏起上臂三角肌下缘中区,进针角度为45°的注射法。1周后观察2组患儿皮下硬结和注射部位疼痛程度。结果观察组硬结发生率为6.25%(3/48),低于对照组32.61%(15/46),差异有统计学意义(P<0.05)。观察组注射时的疼痛程度较对照组轻(P<0.05)。结论上臂三角肌下缘中区45°皮下注射曲普瑞林优于常规皮下注射法,可减少皮下硬结的发生,减轻患儿注射时的疼痛。

Objective To explore the effect of different methods of subcutaneous injection of triptorelin to improve the comfort of children. Methods Totally 94 pediatric patients with idiopathic central precocious puberty were subcutaneously injected with triptorelin. They were randomly divided into the observation group( n = 48) and the control group( n = 46). In the control group,the routine subcutaneous injection was used. The subcutaneous injection with at lower margin of the deltoid was adopted in the observation group. The subcutaneous induration was observed and the pain of the injection site was evaluated. Results The incidence of induration in the observation group was 6. 25%( 3/48),which was lower than that in the control group( 32. 61%( 15/46),with a significant difference( P < 0. 05). Patients in the observation group had a lower pain degree at injection site compared with that of controls( P < 0. 05). Conclusion Subcutaneous injection of triptorelin at lower margin of the deltoid may reduce the incidence of subcutaneous induration and relieve the pain during injection.