前列地尔治疗颅脑损伤后眩晕和头晕的临床疗效观察

Clinical observation on alprostadil in the treatment of vertigo and dizziness after craniocerebral injury

目的:探讨前列地尔治疗轻中度颅脑损伤后眩晕和头晕患者的疗效。方法:收治颅脑损伤后眩晕和头晕患者140例,随机分为试验组80例和对照60例。试验组给予前列地尔联合脑循环电治疗;对照组给予氯化钠注射液联合脑循环电治疗。结果:治疗组有效率87.50%,脑血管痉挛缓解率76.92%;对照组有效率50.00%,脑血管痉挛缓解率28.57%;差异有统计学意义(P<0.05)。结论:应用前列地尔治疗颅脑损伤后眩晕和头晕患者,疗效显著,能明显减轻患者痛苦,缩短患者住院时间。

Objective：To investigate the effect of alprostadil in the treatment of vertigo and dizziness after mild to moderate craniocerebral injury.Methods：140 patients with vertigo and dizziness after craniocerebral injury were randomly divided into the experimental group with 80 cases and the control group with 60 cases.The experimental group were given alprostadil combined with cerebral circulation therapy,while the control group were given sodium chloride injection combined with cerebral circulation therapy.Results：The effective rate of the treatment group was 87.50%,and the rate of cerebral vasospasm relief was 76.92%;the effective rate of the control group was 50%,and the remission rate of cerebral vasospasm was 28.57%;the differences were statistically significant（P0.05）.Conclusion：The curative effect of alprostadil in the patients with dizziness and dizziness after craniocerebral injury is significant.It can obviously reduce the pain of the patients and shorten the time of hospitalization.