IVIM及DKI在乳腺病变的临床研究进展

Magnetic resonance diffusion imaging: Clinical research progress of IVIM and DKI in breast lesions

扩散加权成像(diffusion weighted imaging,DWI)获得的扩散信息存在一定程度的偏移,因此,为更精确描述体内扩散运动及组织微细结构,基于毛细血管微循环灌注的体素内不相干运动(intravoxel incoherent motion imaging,IVIM)模型以及基于非高斯分布的扩散峰度成像(diffusion kurtosis imaging,DKI)模型被相继提出,其相关临床应用也是目前研究的热点。本文主要介绍IVIM及DKI模型的理论基础及二者在乳腺病变中的临床研究进展。

Diffusion weighted imaging （DWI） is a technology to refect the molecular diffusion movement through quantitative water molecular diffusion movement. However the diffusion information from DWI has a certain degree of deviation, in order to more accurately describe the body diffusion movements and microstructure organization, the intravoxel incoherent motion imaging（IVIM） based on the capillary microcirculation perfusion and the diffusion kurtosis imaging（DKI） based on the non-gaussian diffusion is put forward and the relevant clinical application research is the hotspot currently. This article mainly introduce the theoretical basis of IVIM and DKI and the research progresses in breast lesions.