LPS联合AMY、PCT诊断早期急性胰腺炎的价值

The Value of LPS Combined With AMY and PCT in the Diagnosis of Early Acute Pancreatitis

目的探讨血清脂肪酶(LPS)、淀粉酶(AMY)、降钙素原(PCT)联合检测对急性胰腺炎的诊断作用。方法选择我院2016年11月—2017年10月收治的148例急性胰腺炎患者为观察组,另选同期健康体检者70例为对照组,对两组AMY、LPS、PCT水平进行检测,观察单项或联合检测对急性胰腺炎的诊断作用。结果观察组AMY、LPS、PCT水平均较对照组高,差异有统计学意义(P<0.05);三项联合诊断急性胰腺炎早期的灵敏度、特异度及准确率分别为95.27%、100.00%、96.79%,均明显高于单项诊断,差异有统计学意义(P<0.05)。结论血清AMY、LPS、PCT联合检验诊断急性胰腺炎早期的准确性高,也具有较高的特异度及敏感度。

Objective To probe into the diagnostic values of combined detection of serum lipase（LPS）, amylase（AMY） and procalcitonin（PCT） in patients with acute pancreatitis. Methods 148 cases of patients with acute pancreatitis from November 2016 to October 2017 in our hospital were selected as the observation group, other 70 cases of healthy examinees in the same period were selected as the control group. Then, the levels of AMY, LPS and PCT of two groups were detected, and the diagnostic effects of single or combined detection in acute pancreatitis were observed. Results The levels of AMY, LPS and PCT in the observation group were higher than those in the control group, and the difference was statistically significant（P〈0.05）;The sensitivity, specificity and accuracy of three combined diagnosis of acute pancreatitis were respectively 95.27%, 100% and 96.79%,which were significantly higher than that of single diagnosis, the difference was statistically significant（P〈0.05）.Conclusion The combined detection of serum AMY, LPS and PCT in the diagnosis of early acute pancreatitis has high accuracy, high specificity and sensitivity.