奥曲肽联合凝血酶治疗肝硬化合并上消化道出血观察

Observation of Octreotide Combined Thrombin in the Treatment of Liver Cirrhosis Complicated With Upper Gastrointestinal Bleeding

目的探讨肝硬化合并上消化道出血应用奥曲肽联合凝血酶治疗的临床疗效。方法本次研究选取2015年1月—2016年12月在本院治疗的确诊为肝硬化合并上消化道出血的68例患者,将其随机平均分成观察组和对照组,每组34例,所有患者住院后实施基础治疗,所有患者住院后实施基础治疗,观察组的患者给予奥曲肽联合凝血酶进行治疗,对比两组疗效。结果观察组疗效高于对照组(P<0.05)。观察组治疗后止血时间、住院时间、以及再次出血率均优于对照组(P<0.05)。结论肝硬化合并上消化道出血应用奥曲肽联合凝血酶治疗的临床疗效满意。

Objective To investigate the clinical effect of octreotide combined with thrombin in the treatment of hemorrhage of upper gastrointestinal tract in liver cirrhosis. Methods 68 patients with hemorrhage in the upper gastrointestinal tract diagnosed as cirrhosis of the liver from January 2015 to December 2016 were selected, they were randomly divided into observation group and control group, with 34 cases in each group. All patients were treated with basic treatment after hospitalization, and basic treatment was carried out after hospitalization, the observation group were treated with octreotide combined thrombin, and the efficacy of the two groups was compared. Results The effect of the observation group was higher than that of the control group（P〈0.05）. The time of hemostasis, the time of hospitalization and the rebleeding rate of the observation group were all better than those of the control group（P〈0.05）. Conclusion The clinical efficacy of octreotide combined with thrombin in the treatment of liver cirrhosis with upper gastrointestinal bleeding is satisfactory.