临床新生儿呼吸暂停采用呼吸支持与咖啡因的应用探讨

Application of Respiratory Support and Caffeine in Clinical Newborns With Apnea

探讨新生儿呼吸暂停采用呼吸支持及咖啡因应用的相关情况,早产儿脑干呼吸中枢不能成熟地进行新生儿呼吸暂停生理性控制,电解质紊乱及细菌感染等都是新生儿呼吸暂停的重要危险因素。对幼儿加强护理及必要的监护,采取气道压力释放通气、湿化高流量鼻导管通气、经鼻持续气道正压通气及同步间歇指令通气等多种呼吸支持方法,应用枸橼酸咖啡因静脉滴注,使内环境保持相对稳定及提高抗细菌感染能力等对于提高患者临床疗效具有关键性作用。

Neonatal apnea associated with respiratory support and caffeine application, premature infant respiratory centers in the brainstem cannot mature of neonatal apnea physiological control, electrolyte disorder and bacterial infection are important risk factors of neonatal apnea. For infants, we should strengthen nursing and necessary monitoring, adopt airway pressure release ventilation, humidification high flow nasal ventilation, nasal continuous positive airway pressure and synchronous intermittent mandatory ventilation. The application of citric acid caffeine intravenously to keep the internal environment relatively stable and improve the ability of anti bacterial infection has a key role in improving the clinical effcacy of patients.