摘要
目的观察帕金森病应用盐酸美金刚联合用药治疗的临床疗效。方法选取75例帕金森病患者资料分组为A组(35例;多巴丝肼+盐酸多奈哌齐治),B组(40例,多巴丝肼+盐酸美金刚),比较疗效。结果 A组患者治疗后的MMSE量表评分高于B组,差异有统计学意义(P<0.05),A组、B组不良反应发生率对比,差异无统计学意义(P>0.05)。结论盐酸美金刚联合用药治疗帕金森病疗效明显,安全可靠,是重要的治疗方案之一。
Objective To observe the clinical curative effect of the treatment of Parkinson＇s disease by the combination of memantine hydrochloride. Methods 75 patients with Parkinson＇s disease were divided into A group （35 cases; benserazide ＋ donepezil hydrochloride treatment group （B）, 40 cases of Benserazide ＋ memantine hydrochloride）, curative effect comparison. Results The score of MMSE scale in group A was higher than that in group B, and the difference was statistically signifcant （P 〈 0.05）. There was no signifcant difference in the incidence of adverse reactions between group A and group B （P 〉 0.05）. Conclusion Memantine hydrochloride combined with drugs in the treatment of Parkinson＇s disease curative effect is obvious, safe and reliable, is one of the important treatment.
作者
崔艳玲
马同富
常晓春
CUI Yanling;MA Tongfu;CHANG Xiaochun(The First Department of Brain, Cerebral Vascular Hospital of Daqing Oil Field, Daqing Heilongjiang 163003, China)
出处
《中国继续医学教育》
2018年第4期127-128,共2页
China Continuing Medical Education
