夹脊电针配合盐酸青藤碱注射液穴注射治疗骨质疏松骨折下腰痛的临床研究

Clinical Observation of Jiaji Electro-acupuncture Combined with Sinomenine Hydrochloride Injection on low back pain in Osteoporotic Fracture

目的观察夹脊电针配合盐酸青藤碱注射液夹脊穴穴位注射治疗骨质疏松骨折下腰痛的临床疗效。方法将患者99例遵照随机数字表法分为对照组49例和治疗组50例,对照组采用夹脊穴电针加肌肉注射依降钙素加口服钙尔奇碳酸钙d3,治疗组在对照组基础上夹脊穴注射盐酸青藤碱注射液。采用视觉模拟量表(VAS)和改良Oswestry功能障碍指数(ODI)分析疗效,取患者同组治疗前后外周血,采用酶联免疫吸附(ELISA)法检测白介素-1β(IL-1β)及骨保护素(OPG)。结果经3周治疗,治疗组患者外周血OPG较对照组明显升高(P<0.05),IL-1β含量及VAS、ODI评分均较对照组降低(P<0.05),治疗组有效率为86.00%,高于对照组的65.31%(P<0.05)。结论夹脊电针配合盐酸青藤碱穴注射治疗骨质疏松骨折下腰痛临床疗效优于单纯夹脊电针治疗。

Objective： To investigate the therapeutic mechanism and clinical efficacy of Jiaji electro-acupunc- ture combined with acupoint injection of Sinomenine Hydrochloride Injection on low back pain in osteoporotic fracture. Methods： 99 cases with low back pain in osteoporotic fracture were randomly divided into the control group （49 cases） and treatment group（50 cases）. The control group received Jiaji electro-acupuncture plus intra- venous injection of elcatonin ＋ oral Caltrate D3 calcium carbonate. The treatment group on the basis received Jiaji point injection of Sinomenine Hydrochloride Injection. VAS and modified ODI were used to take curative effect analysis.Before and after treatment,peripheral blood was taken from the same group,and detected by ELISA for the detection of IL-I~ and OPG. Results： After 3 weeks＇ treatment,OPG of peripheral blood in the treatment group was significantly higher than that of the control group （P〈 0.05）. The content of IL-1β and scores of VAS and ODI were lower than those of the control group （P〈 0.05）;the efficiency of the treatment group was 86%, higher than that of the control group （65.3%）（P〈 0.05）. Conclusion： Jiaji electroacupuncture combined with Sinomenine Hydrochloride Injectionon low back pain in osteoporotic fracture has a better clinical effect than that of simple Jiaji acupuncture.