木质素模型化合物合成研究的现状与展望

Status and Prospect of Lignin Model Compounds Synthesis

对木质素模型化合物合成研究现状进行了全面的综述。简单介绍了木质素单体合成的3种主要途径:莽草酸途径、苯丙烷类代谢途径及酯还原途径。简述了木质素单体聚合的2种理论,即被学术界广泛接受的随机聚合学说(或自由基组合交联理论)和颇受争议的严格调控聚合学说。阐述了β-O-4、α-O-4、5-5'、β-5'等多种连接键型木质素模型物的二聚体、三聚体及多聚体化学合成方法及机理方面的研究进展,并指出了木质素化学合成过程中的问题及应对措施,明确了木质素模型化合物合成研究的发展方向。

The research status of lignin model compounds synthesis was comprehensively summarized. Three main pathways of lignin monomer synthesis were introduced, including shikimic acid pathway, phenylpropane metabolizing pathway, and ester reduction pathway. The two theories of lignin monomer polymerization were sketched, i.e., the random polymerization theory （or free radical combinatorial coupling theory ） which was widely accepted by academia and the controversial strict regulation polymerization theory. The research development of the chemical synthesis methods and mechanism of dimer, trimer and polymer from lignin model compounds bounded by β-O-4, α-O-4, 5-5＇, and β-5＇ bonds was illustrated. Meanwhile, some problems and countermeasures during the lignin chemical synthesis process were pointed out and the development direction of lignin model compounds synthesis research was confirmed.