肌层浸润性膀胱癌保留膀胱的综合治疗策略

Comprehensive therapy of bladder preservation for muscle invasive bladder cancer

膀胱癌是泌尿系常见的恶性肿瘤,其中肌层浸润性膀胱癌的标准治疗方案是膀胱根治性切除术,但该手术对于患者自身及术后生活均会造成巨大的影响。对此,不少国内外学者指出部分合适的患者可以选择以保留膀胱的手术为主,同时辅以放射治疗、化学治疗等辅助性治疗的综合治疗方案,术后对患者进行密切的随访,其疗效同根治性膀胱切除术相近,且手术风险及并发症的发生率也显著低于根治性膀胱切除术,而患者则可以保留有功能的膀胱。

The bladder cancer is a common malignant tumor in urinary system. The standard treatment for muscle invasive bladder cancer is radical cystectomy. Considering the damage to patients and the drastic effect on their life caused by the radical cystectomyi many domestic and overseas scholars suggest a comprehensive treatment based on a bladder-keeping surgery with adjuvant therapy including radiotherapy, chemotherapy and frequent follow-up, which showslow operation-related risk and complication rate compared with the radical cystectomy. As a result, patients are able to preserve the function of bladder.