摘要
目的探讨乌鲁木齐某社区维吾尔族(维)、汉族血清维生素D水平与肥胖的相关性。方法 2013年5月采用横断面方法随机抽取乌鲁木齐某社区1546例常住居民,维族726例(男/女=196/530,平均年龄43.63±12.90岁)、汉族820例(男/女=279/541,平均年龄44.19±12.88岁)。测定血清25-羟维生素D[25(OH)D]水平,测量身高、体重、颈围(NC)、臀围、腰围(WC),并计算腰臀比(WHR)、腰围身高比(WHt R)和体重指数(BMI)。结果维族血清25(OH)D水平(12.82±7.15ng/ml)明显低于汉族(18.99±8.00ng/ml,P<0.05),两民族间维生素D缺乏(维86.0%、汉61.1%)、不足(维10.5%、汉29.6%)、充足(维3.6%、汉9.3%)的检出率比较,差异均有统计学意义,两民族间正常体重(维25.1%、汉42.2%)、肥胖(维41.2%、汉19.1%)的检出率比较,差异均有统计学意义。该研究人群中,血清25(OH)D水平与臀围、WC、WHt R、BMI呈负相关(P均<0.05);在18~44岁维族女性人群中,血清25(OH)D水平与臀围、WC、WHt R呈负相关(P均<0.05);在45~60岁维族男性人群中,血清25(OH)D水平与臀围呈负相关(P=0.004);在各年龄段汉族人群及≥60岁维族人群中血清25(OH)D水平与肥胖指标均无相关性(P均>0.05)。结论乌鲁木齐某社区维、汉族均存在普遍的维生素D缺乏及明显的超重肥胖现象,血清25(OH)D水平与多个肥胖指标呈负相关,尤其在维族青年女性人群中明显,提示维生素D缺乏可能与肥胖相关。
Objective To explore the relationship between serum vitamin D level and obesity in Uygur and Han in a Urumqi community. Methods A cross-sectional survey was performed in 2080 permanent residents in Urumqi,Xinjiang in May,2013.Among them, 1546 cases whose date were complete were included in this study, with Uygur 726 (male/female:196/530, average age 43.63±12.90 years old), Han 820 (male/female=279/541, average age 44.19±12.88 years old). Determination of serum 25-hydroxy vitamin D[(25(OH)D] level, measure height, weight, neck circumference (NC), hip circumference, waist circumference (WC),and calculation waist to hip ratio (WHR),waist to height ratio (WHtR), body mass index (BMI) was performed. Results The serum 25(OH)D levels of Uygur (12.82±7.15ng/ml) were significantly lower than that of Han (18.99±8.00ng/ml) (P〈0.05). There was a statistically significant difference in the percentage of vitamin D deficiency (Uygur 86.0%, Han 61.1%),vitamin D insufficiency (Uygur 10.5%, Han 29.6%) and vitamin D sufficiency (Uygur 3.6%, Han 9.3%) between Uygur and Han nationality. There was a statistically significant difference in the percentage of normal weight (Uygur 25.1%, Han 42.2%), obesity (Uygur 41.2%, Han 19.1%)between Uygur and Han nationality. The study population, serum 25(OH)D levels were negatively(P〈0.05)associated with hip circumference, WC, WHtR, BMI. In 18-44 years old female Uygur population, serum 25(OH)D levels were negatively(P〈0.05)associated with hip circumference, WC, WHtR. In 45 to 60 years old Uygur male population, serum 25(OH)D levels were negatively associated with hip circumference(P=0.004). In Han and greater than 60 years old Uygur population, serum 25(OH)D levels and obesity indices were not correlated. Conclusion Both Uygur and Han have vitamin D deficiency generally and obvious obesity and overweight in a Urumqi community, serum 25(OH) D levels and obesity index showed negative correlation, especially in 18-44 years old female Uygur population, suggesting that vitamin D deficiency may be associated with obesity.
出处
《医学研究杂志》
2018年第1期123-127,共5页
Journal of Medical Research
基金
新疆维吾尔自治区乌鲁木齐市天山区科学计划项目基金资助项目(20120101)
新疆维吾尔自治区人民医院院内基金资助项目(20140102)