2016年成都市首例人感染H5N1禽流感病例调查报告

Survey Report on the First Case of Human Infection of H5N1 Avian Influenza in Chengdu in 2016

目的对成都市2016年首例人感染H5N1禽流感病例进行现场流行病学调查,探索可能感染来源,为进一步认识和防制人感染H5N1禽流感提供科学依据。方法运用描述流行病学方法对病例开展流行病学调查,并采集病例、密切接触者、从业人员暴露者及相关环境标本进行检测分析。结果该例人感染H5N1禽流感病例于2016-01-13确诊,经积极抢救治疗无效,于2016-02-16死亡;发病前有明确禽类(活禽交易市场)暴露史;溯源调查及采样检测发现,疫情涉及相关场所环境禽流感病毒污染严重;58例密切接触者及92例暴露人员经7 d医学观察无发热等症状,未发现人与人之间的传播证据。结论成都市2016年首例人感染H5N1禽流感病例属于散发病例,未发现人传人现象,感染途径可能为禽到人或禽环境到人。

Objective To carry out a field epidemiological survey on the first case of human infection of H5 N1 avian influenza in Chengdu in 2016,explore potential source of infection and provide a basis for further understanding and prevention of human infection of H5 N1 avian influenza. Methods Descriptive epidemiology methods were used to survey the case. Meanwhile,samples of the patient and people in close contact with the patient,related environmental samples and samples of related workers exposed were collected and assayed.Results The above-mentioned case of human infection of H5 N1 avian influenza was established on January 13,2016. Positive rescue failed,and the patient died on February 16,2016. The patient had a clear history of exposure to poultry（ live-bird trading market）. Tracing investigation and sample assay revealed that those sites related to the epidemic situation were polluted severely by avian influenza virus. Evidence on person to person transmission has not been discovered for no such symptoms as fever were found among 58 close contacts and 92 exposed people. Conclusion Person to person transmission has not been discovered,so the first case of human infection of H5 N1 avian influenza in Chengdu in 2016 was deemed a sporadic case. The origin of infection may be poultry or poultry related environment.