2015年攀枝花市健康人群风疹抗体阳性率监测分析

Rubella Antibody Levels in Healthy People in Panzhihua City in 2015

目的了解攀枝花市健康人群风疹抗体水平,为评估风疹疫情风险,调整免疫策略提供依据。方法在攀枝花市所有5个县(区)分别随机抽取7个年龄组,各组不少于20名健康人群作为抗体监测对象,用酶联免疫吸附法检测风疹IgG抗体。结果共采集有效血清样本681份,风疹IgG抗体阳性率平均71.95%;不同性别、民族、户籍地、居住地类别人群风疹IgG抗体阳性率差异不明显,不同县区、不同年龄段、不同接种情况人群抗体阳性率差异有统计学意义。结论攀枝花市健康人群风疹IgG抗体水平较低,人群免疫屏障脆弱,输入性病例引起风疹暴发疫情的风险值得警惕;应加强风疹疫苗的基础免疫,并确保MMR的高接种率;育龄妇女感染风疹风险较大,应进一步加强对育龄期女性风疹疫苗接种的推动工作。

Objective To investigate the rubella antibody levels among the healthy people in Panzhihua city,evaluate the risk of rubella epidemic statues and provide the evidence for immunization strategy regulation.Methods seven groups were random enrolled from 5 counties/districts of Panzhihua city. There were 20 healthy cases at least in each group as the monitoring objects. And ELISA technique was used to detect the rubella IgG antibodies. Results There were 681 valid serum samples collected with 71. 95% average positive rate of rubella IgG antibody. The differences of positive rate of rubella IgG antibody among the different gender,ethnic,domicile,residence were not significant. The differences of positive rate of rubella IgG antibody among different counties,different age groups and vaccinating situation were significant. Conclusion The rubella IgG antibody is on low level. But immunologic barrier was fragile with high risk of rubella outbreak caused imported cases.The primary immunization of rubella vaccine should be strengthened with high vaccination rate of MMR. And the rubella vaccination in fertile women should be strengthened.