早产产前糖皮质激素的使用

Use of antenatal corticosteroids for premature birth

早产是全球范围内围产期新生儿死亡率和发病率高的主要问题。早产孕妇产前接受糖皮质激素治疗后可以有效降低早产儿呼吸窘迫综合征、脑室内出血和坏死性小肠结肠炎等的发生率。但世界各国关于产前糖皮质激素的使用略有不同,文章就现有产前糖皮质激素使用的循证医学证据做一总结,以期指导临床实践。

Preterm birth is a main cause of high perinatal neonatal mortality and morbidity in the world.The incidence of respiratory distress syndrome,intraventricular hemorrhage and necrotizing enterocolitis in premature infants can be effectively reduced by using antenatal corticosteroids.The use of antenatal corticosteroids varies across different countries,so we summed up the evidence-based proof in the use of glucocorticoids to guide clinical practice.