中青年与老年直肠癌患者的临床及病理特征差异分析

Analysis of Clinical and Pathological Features of Middle-aged and Young Patients with Rectal Cancer

目的:分析中青年与老年直肠癌患者的临床及病理特征差异。方法:将笔者所在医院2009年9月-2016年5月收治的105例直肠癌患者进行临床分析,47例为中青年组,58例为老年组;比较两组患者临床资料、病理特征和随访资料,观察其生存情况。结果:两组患者性别比例、Dukes分期、生存时间和三年生存率比较差异均无统计学意义(P>0.05);两组患者遗传史发生率、发病到确诊时间、便秘发生率、初始症状、肿瘤位置、组织学分类和分化情况比较差异均有统计学意义(P<0.05)。结论:中青年患者病情发现晚、初始症状与老年患者差异较大,若及时诊治,两者预后则无明显差异。

Objective： To analyze the clinical and pathological characteristics of middle-aged and elderly patients with rectal cancer.Method： The clinical analysis of 105 patients with rectal cancer treated by our hospital from September 2009 to May 2016 were analyzed, and 47 cases were in the middle youth group.The 58 cases were aged The clinical data, pathological features and follow-up data of the two groups were compared to observe its survival.Result： There was no significant difference between the two groups of patients in terms of sex ratio, Dukes staging, survival time and three-year survival rate （P〉0.05）.There was a significant difference between the two groups of patients with the incidence of genetic history, the time of diagnosis, the incidence of constipation, initial symptoms, tumor location, histological classification and differentiation （P〈0.05）.Conclusion： The prognosis of young and middle-aged patients is significantly different from that of elderly patients, and the prognosis of the two patients is no significant difference.