血清PG检测在胃癌早期筛查及术后监测中的应用

Serum PG Detection was Used in Early Screening and Postoperative Monitoring of Gastric Cancer

目的:探讨血清PG检测在胃癌早期筛查及术后监测中的应用价值。方法:选取笔者所在医院2016年5月-2017年5月收治的胃癌患者86例,行全胃切除术者29例,为胃癌全胃切除术组,同时选取同期于笔者所在医院进行体检的健康人82例作为对照组,以胶乳免疫比浊法对所有患者血清PG含量进行检测,并对比检测结果。结果:胃癌患者血清PGⅠ含量和PGⅠ/PGⅡ比值远低于健康对照组,差异均有统计学意义(P<0.05);胃癌全胃切除术组患者血清PGⅠ、PGⅡ含量远低于胃癌组患者,差异有统计学意义(P<0.05);术后复发组患者血清PGⅠ、PGⅡ含量远高于术后未复发组患者,差异有统计学意义(P<0.05)。结论:血清PG检测对胃癌早期筛查具一定指导作用,同时也可对胃癌术后复发情况进行监测,具较高应用价值。

Objective： To explore the value of serum PG detection in early screening and postoperative monitoring of gastric cancer.Method： 86 cases of gastric cancer treated by our hospital from May 2016 to May 2017 were selected, at the same time, the healthy people who had the same time in our hospital were selected as the control group, the serum PG content of all patients was detected with the latex immunity and turbidity method, and the results were compared. Result： Gastric cancer patients with total gastrectomy group serum PG I, PG I1 content is far lower than the patients with gastric cancer group, Statistical significance （P〈0.05）; The difference between statistical significance （P〈0.05）; Postoperative recurrence patients serum PG I, PG II content is much higher than the group of patients, no postoperative recurrence statistical significance difference （P〈0.05）.Conclusion： The serum PG test can guide the early screening of gastric cancer, and it can also be used to monitor the recurrence of gastric cancer.