期刊文献+

血管紧张素受体脑啡肽酶抑制剂在心力衰竭治疗中的研究进展及展望 被引量:52

下载PDF
导出
摘要 血管紧张素受体脑啡肽酶抑制剂(ARNI)是最新研发出的心力衰竭治疗药物。多项临床研究显示ARNI可以改善症状、改善预后,降低心力衰竭死亡率,最新欧美心力衰竭指南也均推荐其用于射血分数降低的心力衰竭(HFr EF)的治疗。本文就ARNI在心力衰竭治疗中的作用机制、研究历程及展望做一简要阐述。
出处 《中国循环杂志》 CSCD 北大核心 2018年第2期195-198,共4页 Chinese Circulation Journal
  • 相关文献

参考文献3

二级参考文献35

  • 1McMurray JJ, Packer M, Desai AS, et al. Baseline characteristics and treatment of patients in prospective cmnparison of ARNI with ACEI to determine impact on global mortality and morbidity in heart failure trial (PARADIGM-HF). Eur J Heart Fail, 2014, 16: 817-825.
  • 2Packer M, McMurray JJ, Desai AS , et al. Angiotensin Receptor Neprilysin Inhibition Compared With Enalapril on the Risk of Clinical Progression in Surviving Patients With Heart Failure. Circulation, 2015, 131: 54-61.
  • 3McMurray J, Packer M, Desai A, et al. A putative placebo analysis of the effects of LCZ696 on clinical outcomes in heart failure. Eur Heart J, 2015, 36: 434-439.
  • 4von Lueder TG, Wang BH, Kompa AR, et al. Angiotensin Receptor Neprilysin Inhibitor LCZ696 Attenuates Cardiac Remodeling and Dysfimction After Myocardial Infarction by Reducing Cardiac Fibrosis and Hypertrophy. Circ Heart Fail, 2015, 8: 71-78.
  • 5Bavishi C, Messerli FH, Kadosh B, et al. Role of neprilysin inhibitor combinations in hypertension: insights from hypertension and heart failure trials. Eur Heart J, 2015, 36: 1967-1973.
  • 6McMurray JJ, Packer M, Desai AS, et al. Angiotensin-neprilysin inhibition versus enalapril in heart failure. N Engl J Med, 2014, 371: 993 - 1004.
  • 7Vardeny O, Miller R, Solomon SD. Combined neprilysin and renin- angiotensin system inhibition for the treatment of heart failure. JACC Heart Failure, 2014, 2:663 - 670.
  • 8McMurray J J, Packer M, Desai AS, et al. Dual angiotensin receptor and neprilysin inhibition as an alternative to angiotensin-converting enzyme inhibition in patients with chronic systolic heart failure: rationale for and design of the Prospective comparison of ARNI with ACEI to Determine Impaet on Global Mortality and morbidity in Heart Failure trial (PARADIGM-HF). EurJ Heart Fail, 2013, 15: 1062-1073.
  • 9Fitippatos G, Farmakis D, Parissis J, et al. Drug therapy for patients with systolic heart failure after the PARADIGM-HF trial: in need of a new paradigm of LCZ696 implementation in clinical practice. BMC Med, 2015, 13: 35.
  • 10Ruilope LM, Dukel A, Behm M, et al. Blood-pressure reduction with LCZ696, a novel dual-acting inhibitor of the angiotensin Ⅱ receptor and neprilysin: a randomised, double-blind, placebo-controlled, active comparator study. Lancet, 2010, 375: 1255-1266.

共引文献4708

同被引文献337

引证文献52

二级引证文献647

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部