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头孢哌酮-舒巴坦对脑卒中患者伴肺部感染的疗效及其对血清炎症因子水平和细菌清除的影响 被引量:2

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摘要 目的:评价头孢哌酮-舒巴坦对脑卒中患者伴肺部感染的疗效及其对血清炎症因子水平和细菌清除的影响。方法:选取2013年1月—2017年3月期间收治的脑卒中伴肺部感染患者60例资料,将其随机分为观察组与对照组,每组30例;对照组患者给予头孢他啶治疗,观察组患者给予头孢哌酮-舒巴坦治疗,比较两组患者治疗后的总有效率、细菌清除率和治疗期间的不良反应发生率差异,以及治疗前后血清炎症因子水平测得值的变化情况。结果:观察组患者治疗后的总有效率高于对照组(P<0.05);治疗前两组患者的白细胞计数(WBC)、C-反应蛋白(CRP)和降钙素原(PCT)水平测得值经比较其差异均无统计学意义(P>0.05),治疗后观察组患者的WBC、CRP和PCT水平测得值均低于对照组(P<0.05);观察组患者治疗后细菌清除率高于对照组(P<0.05);两组患者治疗期间的不良反应发生率经比较其差异无统计学意义(P>0.05)。结论:采用头孢哌酮-舒巴坦治疗脑卒中患者伴肺部感染的临床疗效较为确切,有效改善了患者的血清炎症因子水平,提高了细菌的清除率。
作者 刘煜帆
出处 《抗感染药学》 2017年第9期1781-1783,共3页 Anti-infection Pharmacy
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