翼状胬肉切除联合角膜缘干细胞移植术对视力和屈光状态的影响

Effect of pterygium excision combined with limbal stem cell transplantation on visual acuity and refraction

目的探讨翼状胬肉切除联合角膜干细胞移植术对翼状胬肉患者视力及屈光状态的影响。方法选取2014年9月~2016年12月期间在本院收治的106例(106眼)翼状胬肉患者,按照所行术式的不同将其分为观察组和对照组,观察组54例(54眼),对照组52例(52眼),对照组单纯行翼状胬肉切除术,观察组行以翼状胬肉切除联合角膜干细胞移植术,记录比较两组患者手术前后的视力水平、角膜散光度。结果两组患者术后1周、2周、3周的视力水平较术前明显改善,角膜散光度较术前明显降低,且术后1周、2周、3周观察组患者的视力水平及角膜散光度明显优于对照组患者,差异具有统计学意义(P<0.05)。结论翼状胬肉切除联合角膜干细胞移植术治疗翼状胬肉可有效提高患者视力水平,改善患眼屈光状态,值得推广应用。

Objective To investigate the effect of pterygium excision combined with corneal stem cell transplantation on the visual acuity and refraction of pterygium patients.Methods From September 2014 to December 2016 in our hospital 106 cases(106 eyes) of pterygium patients,according to the operation they were divided into the observation group and the control group,the observation group of 54 cases(54 eyes),the control group of 52 cases(52 eyes),the control group only underwent pterygium meat resection,the observation group underwent pterygium excision combined with limbal stem cell transplantation,records of two groups were compared before and after surgery,visual acuity corneal astigmatism.Results Two groups of patients after 1 weeks,2 weeks and 3 weeks of visual acuity significantly improved compared with preoperative,the degree of corneal astigmatism was significantly lower than that before the operation,and after 1 weeks,2 weeks and 3 weeks to observe the visual acuity and astigmatism degree group were significantly better than the control group,the difference was statistically significant(P<0.05).Conclusion Pterygium excision combined with corneal stem cell transplantation in the treatment of pterygium can effectively improve the vision level and improve the refractive status of eyes,which is worthy of popularization and application.