SRM-IV前庭功能诊疗系统联合维生素D治疗良性阵发性位置性眩晕的临床疗效评价

Evaluation of SRM-IV system combined with vitamin D in treatment of benign paroxysmal positional vertigo

目的探讨SRM-IV诊疗系统联合维生素D治疗良性阵发性位置性眩晕(BPPV)的临床疗效。方法将317例原发性BPPV患者随机分为4组:SRM-IV诊断复位组+维生素D(n=83);SRM-IV诊断复位组+安慰剂(n=77);手法诊断复位组+维生素D(n=80);手法诊断复位组+安慰剂(n=77)。治疗6个月时评价其疗效(痊愈、有效、无效),并记录眩晕复发情况。结果 4组患者疗效比较,差异无统计学意义(P>0.05),但眩晕复发患者比较,差异有统计学意义(P<0.05);SRM-IV诊断复位眩晕复发患者<手法诊断复位患者(P<0.05);补充维生素D与未补充维生素D比较,眩晕复发患者呈下降趋势,但差异无统计学意义(P>0.05)。结论 SRM-IV诊疗系统疗效确切,降低BPPV复发,增加患者诊治的依从性,为BPPV规范化诊治提供理论依据。

Objective To observe the clinical effect of the automatic vestibular function diagnosis and therapy system （SRM-IV） combined with vitamin D in the treatment of benign paroxysmal positional vertigo （BPPV）. Methods A total of 317 primary BPPV patients were randomly divided into groups of SRM-IV ＋ vitamin D （n = 83）, SRM-IV ＋ placebo （n = 77）, repositioning maneuver ＋ vitamin D （n = 80）, and repositioning maneuver ＋ placebo （n = 77）. The follow-up period was 6 months. The evaluation of therapeutic results included recovery, effective therapy, and useless therapy. Results The evaluation of therapeutic results of the four groups had no statistical difference （P 〉 0.05）, but there were differences in the recurrence of BPPV （P 〈 0.05）. There was decreased recurrence of BPPV in SRM-IV treatment group than that in repositioning maneuver group （P 〈 0.05）. Although there was tendency that supplemental vitamin D can decrease recurrence of BPPV, there were no statistical differences （P 〉 0.05）. Conclusion SRM-IV has a defnite curative effect on BPPV, which can reduce the frequency of vertigo recurrence and increase patient compliance. Our results provide an underlying theoretical basis for the prevention and treatment of BPPV.