摘要
目的探讨双支架辅助弹簧圈栓塞颅内大型动脉瘤的安全性和有效性。方法颈内动脉床突段和后交通段,椎动脉大型动脉瘤共22例,应用双LVIS支架栓塞12例,enterprise支架辅助弹簧圈栓塞10例,统计动脉瘤致密栓塞程度,术中动脉瘤破裂率,支架内血栓率,动脉瘤复发率,载瘤动脉是否狭窄。结果 22例动脉瘤,应用LVIS支架致密栓塞率93.3%(10/12),术中动脉瘤破裂率8.3%(1/12),载瘤动脉通畅率100%,术中支架血栓率8.3%(1/12);enterprise支架致密栓塞率90%(9/10),载瘤动脉通畅率100%,术中动脉瘤破裂率10%(1/10),术中支架血栓率10%(1/10)。随访0.5~5年2组动脉瘤均未见复发,载瘤动脉均未见狭窄,预后良好率分别为91.67%、90%,2组比较差异无统计学意义(P>0.05)。结论应用双支架辅助弹簧圈栓塞能够提高颅内大型动脉瘤致密栓塞率,降低复发率,安全有效。
Objective To investigate the therapeutic effects and safety of double-stent-assisted coil embolization on intracranial large aneurysms. Methods Twenty-two patients with large aneurysm were enrolled in the study,12 patients of them were treated by double LVIS stents embolization（ group A）,however,the other 10 patients were treated by enterprise stent-assisted coil embolization（ group B）. The degree of dense embolization of aneurysm,intraoperative aneurysm rupture rate,stent thrombosis rate,aneurysm recurrence rate,narrow status of tumor artery were statistically analyzed and compared between two groups. Results In group A the dense embolization rate was 93. 3%（ 10/12）,intraoperative aneurysm rupture rate was 8. 3%（ 1/12）,patency rate of tumor artery was 100% and intraoperative stent thrombosis rate was 10%（ 1/10）,however,in group B dense embolization rate was was 90%（ 9/10）,patency rate of tumor artery was 100%,intraoperative aneurysm rupture rate was 10%（ 1/10）,intraoperative stent thrombosis rate was 10%（ 1/10）. After 0. 5 ~ 5 years follow up,no relapse of aneurysms was found in both groups,also no narrow of tumor artery was found. Moreover the excellent and good rate of prognosis in the two groups was 91. 67% and 90%,respectively,there was no significant difference between two groups（ P 〉0. 05）. Conclusion The double-stent-assisted coil embolization can improve the dense embolization rate in treatment of intracranial large aneurysms,and can reduce the relapse rate,with safety and effectiveness.
出处
《河北医药》
CAS
2018年第3期384-388,共5页
Hebei Medical Journal
基金
河北省科学技术研究与发展指导计划项目(编号:132777242)
