深圳市高龄不孕女性焦虑和抑郁症状及相关因素分析

Prevalence and associated factors analysis of anxiety and depression of infertile women with older age in Shenzhen

目的:了解深圳地区高龄不孕女性人群焦虑和抑郁情况,探索影响焦虑和抑郁症状的相关因素。方法:2016年1月—12月对深圳市人民医院不孕不育门诊就诊的年龄35~45岁女性不孕症患者210例开展横断面研究,通过医院焦虑抑郁量表调查研究对象焦虑和抑郁症状,并用SPSS软件分析相关的影响因素。结果:调查对象中有焦虑症状81例(38.6%),抑郁症状83例(39.5%)。多因素分析显示,已有子女(OR=0.67,95%CI0.53~0.93),家庭月收入>8000元(OR=0.72,95%CI0.58~0.94)是焦虑的保护因素;对于抑郁的形成,原发性不孕(OR=1.89,95%CI1.19~2.72)是危险因素,高中及以上文化程度(OR=0.54,95%CI0.32~0.91)、家庭的支持(OR=0.42,95%CI0.29~0.61)是保护性因素。结论:深圳市35岁以上不孕女性焦虑和抑郁症状发生率较高,应该引起关注,对于不孕女性应进行常规心理健康问题的筛查,早期给予社会支持和心理关怀。

Objective：To investigate the situation of anxiety and depression among infertile women with older age in Shenzhen and to explore the associated factors that influenced on anxiety and depression.Methods：210 infertile women（35-45 years old）from the infertility clinical outpatients service of Shenzhen people’s hospital were recruited in this cross-sectional survey between January 2016 and December 2016.General demographic and clinical information were collected by patient interview.Situation of anxiety and depression of included infertile women was assessed by Chinese version of hospital anxiety and depression scale.Prevalence and associated protective or risk factors were analyzed by SPSS.Results：In all included infertile women,81（38.6%）women were screened positive for anxiety and 83（39.5%）had depressive symptoms.Multivariate analysis indicated that women with children[odds ratio（OR）0.67,95%confidence interval（CI）0.53-0.93]and higher incomes（OR 0.72,95% CI 0.58-0.94）were protective factors to anxiety.Primary infertility was associated with increased depressive symptoms（OR 1.89,95% CI 1.19-2.72）.Higher education level（OR 0.54,95% CI 0.33-0.91）and family support（OR 0.42,95% CI 0.29-0.61）were protective factors to depression.Conclusion：Anxiety and depression remain highly prevalent in infertile women with age≥35 years old in Shenzhen,so it is should be paid more attention to.Regular mental health screening for all infertile patients,social support,and psychosocial care are very important for infertile women.