四联疗法治疗幽门螺杆菌相关性慢性胃炎的临床研究

Clinical Study on Treating Helicobacter Pylori Associated Chronic Gastritis With Quadruple Therapy

目的分析四联疗法治疗幽门螺杆菌相关性慢性胃炎的临床疗效。方法抽取2014年1月—2016年12月我院收治的84例幽门螺杆菌相关性慢性胃炎患者作为研究对象。将其随机分为两组,每组各42例。研究组选择四联疗法,对照组选三联疗法,对比两组患者的治疗效果。结果研究组治疗有效率及幽门螺杆菌转阴率均高于对照组,差异具有统计学意义(P<0.05);不良反应发生率低于对照组,但组间对比,差异无统计学意义(P>0.05)。结论四联疗法治疗幽门螺杆菌相关性慢性胃炎疗效显著。

Objective To analyze the clinical efficacy of quadruple therapy in the treatment of Helicobacter pylori associated chronic gastritis. Methods 84 cases of Helicobacter pylori associated chronic gastritis treated in our hospital from January 2014 to December 2016 were selected as the study subjects. They were randomly divided into two groups, 42 cases in each group. The study group selected the quadruple therapy, the control group selected the triple therapy, compared the treatment effect of the two groups. Results The effective rate of treatment and the negative rate of Helicobacter pylori were higher in the study group than in the control group, and the difference was statistically significant（P 〈 0.05）. The incidence of adverse reactions was lower than that of the control group, but there was no significant difference between the groups（P 〉 0.05）. Conclusion Quadruple therapy is effective in the treatment of Helicobacter pylori associated chronic gastritis.