白细胞、降钙素原联合C-反应蛋白在COPD患者细菌感染中的诊断价值

The Value of WBC, PCT Combined With CRP in Bacterial Infection in COPD Patients

目的探析联合检测WBC计数、降钙素原及C反应蛋白在慢性阻塞性肺疾病细菌感染中的诊断价值。方法选择我院73例COPD患者作为研究对象,按是否存在细菌感染,将其分为细菌感染组(n=33)和非细菌感染组(n=40),另选同期35例健康体检者为正常对照组,均进行白细胞、降钙素原以及C-反应蛋白检测。结果细菌感染组WBC、PCT、CRP水平高于非细菌感染组和正常对照组,差异具有统计学意义(P<0.05);且非细菌感染组PCT、CRP值高于正常对照组,差异具有统计学意义(P<0.05);在细菌感染组中,WBC、PCT、CRP联合检测的敏感度为93.94%、特异度为90.91%,均优于WBC、PCT、CRP单一检测,差异具有统计学意义(P<0.05)。结论WBC、PCT、CRP联合检测应用于COPD细菌感染中具有较高的临床诊断价值。

Objective To investigate the diagnostic value of WBC,PCTand CRP inbacterial infection in COPD patients. Methods 73 patientswith COPD were divided into infection group （n=33） and non-infection group （n=40）, and 35 healthy persons in the same period as control groupwere treated with WBC, PCT and CRP detection. Results The levels of WBC,PCT and CRP in the infected group were higher than non-infected group and control group,the difference was statistically significant （P 〈 0.05）; the level of PCT and CRP in the non-infected group was higher than control group, the difference was statistically significant （P 〈 0.05）; the sensitivity of combined detection WBC, PCT, CRP was 93.94 %, specifcity of 90.91%, were significantly better than single detection, the difference was statistically significant （P 〈 0.05）. Conclusion Combined detectionof WBC,PCT and CRP in COPD bacterial infection has a high clinicaldiagnostic value.