硫酸镁和甲基强的松龙治疗重症支气管哮喘的临床效果研究

Clinical Effect of Magnesium Sulfate and Methylprednisolone in the Treatment of Severe Bronchial Asthma

目的对重症支气管哮喘患者采用硫酸镁和甲基强的松龙治疗的效果进行分析和讨论。方法本次研究对象均为我院2012年1月—2017年10月接收的重症支气管哮喘患者,采用随机平均原则将其分为对照组和研究组,各39例,对两组患者治疗效果以及治疗前后1 s用力呼气量(FEV_1)、最大呼吸量(PEF)以及用力肺活量(FEV)进行比较。结果对照组治疗总有效率是76.92%,研究组治疗总有效率是94.87%,研究组高于对照组,差异有统计学意义(P<0.05)。结论将硫酸镁联合甲基强的松龙应用于重症支气管哮喘患者治疗之中,在提升患者治疗效果的同时,也能够缓解患者肺部功能状况。

] Objective To analyze and discuss the effect of Magnesium Sulfate and methylprednisolone in the patients with severe bronchial asthma. Methods The subjects were all severe bronchial asthma patients admitted from January 2012 to October 2017 in our hospital. They were randomly divided into control group and research group, with 39 cases in each group. The treatment effect of the two groups and the 1 s forced expiratory volume （FEV1）, the maximum breathing volume （PEF） and the forced vital capacity （FEV） were compared before and after the treatment. Results The total effective rate in the control group was 76.92%, and the total effective rate in the study group was 94.87%. The study group was higher than the control group, and the difference was statistically signifcant （P 〈 0.05）. Conclusion The combination of magnesium sulfate and methylprednisolone in the treatment of severe bronchial asthma can improve the therapeutic effect of patients while relieving the lung function of patients.