联合使用噻托溴铵和沙美特罗替卡松治疗慢性阻塞性肺疾病43例

Combined Use of Tiotropium Bromide and Salmeterol Fluticasone in the Treatment of 43 Cases of Chronic Obstructive Pulmonary Disease

目的分析对慢性阻塞性肺疾病患者行以噻托溴铵和沙美特罗替卡松联合治疗的临床效果。方法择取2016年8月—2017年10月我院收治的86例慢性阻塞性肺疾病患者进行研究,随机将所选患者分为对照组和研究组,对照组行噻托溴铵治疗,研究组行噻托溴铵和沙美特罗替卡松联合治疗,对两组临床效果进行分析和比较。结果治疗前两组FEV_1、FVC、FEV_1/FVC比较均差异无统计学意义,治疗后研究组FEV_1、FVC、FEV_1/FVC均高于对照组(P<0.05)。结论对慢性阻塞性肺疾病患者行以噻托溴铵和沙美特罗替卡松联合治疗效果良好。

Objective To analyze the clinical effect of combined therapy with tiotropium bromide and salmeterol futicasone in patients with chronic obstructive pulmonary disease. Methods The study was performed in 86 cases of COPD who were selected from August 2016 to October 2017 in our hospital, and randomly divided into control group and study group. The control group received tiotropium bromide, study group received tiotropium bromide and salmeterol futicasone, the clinical effect of two groups were analyzed and compared. Results There was no significant difference in FEV1, FVC and FEV1/FVC between the two groups before treatment. The FEV1, FVC and FEV1/FVC in the study group were higher than those of the control group after treatment （P 〈 0.05）. Conclusion The combination of thiotropium bromide and salmeterol futicasone in the patients with chronic obstructive pulmonary disease has good effect.