表皮生长因子联合超声治疗肾造瘘口的临床研究

The clinical research of epidermal growth factor combined with ultrasonic in treatment of kindney stoma

目的探讨表皮生长因子联合超声治疗肾造瘘口的临床效果。方法将我院收治的80例行经皮肾镜碎石造瘘手术的患者随机分为2组,对照组按常规方法局部处理肾造瘘口,观察组在常规处理基础上使用表皮生长因子凝胶外涂肾造瘘口联合超声治疗。观察2组患者治疗后伤口细菌数和细菌清除率、造瘘口愈合时间及临床疗效。结果经治疗后2 h观察组细菌数明显少于对照组(P<0.05),观察组细菌清除率则明显高于对照组(P<0.05)。观察组造瘘口愈合时间明显短于对照组(P<0.05)。观察组治疗有效率明显高于对照组(P<0.05)。结论表皮生长因子联合超声治疗肾造瘘口效果显著,值得临床推广。

Objective To investigate the clinical effect of epidermal growth factor combined with ultrasonic intreatment of kindney stoma. Methods 80 case of treated by percutaneous nephrolitholomy in our hospital were randomydivided into two groups.The control group treated with conventional method, and the observation group treated withepidermal growth factor combined with ultrasonic.The number of wound bacteria, bacterial eradication rate,healing timeof stoma and effecacy were observated in the two goups. Results After the treatment of 2 hours, the number of woundbacteria in the observation group was less than that in the control group （P〈0.05）, and the bacterial eradication rate in theobservation group was higher than that in the control group（P〈0.05） .The healing time of stoma in the observation groupwas shorter than that in the control group（P〈0.05）, and the efficacy rate in the observation group was higher than that inthe control group（P〈0.05） .Conclusion The effect of epidermal growth factor combined with ultrasonic in treatment ofkindney stoma was significant, which should be widely applied.