慢性牙周炎伴高血脂病人牙周治疗后血脂水平的变化

Clinical study on the change of serum lipid level in patients with chronic periodontitis complicated with high blood lipid after treatment

目的:研究慢性牙周炎伴高血脂病人牙周治疗后血脂水平变化。方法:选取确诊为伴有慢性牙周炎的高血脂病人65例,通过随机数表法将所有病人分为观察组(32例)和对照组(33例)。对照组给予口腔卫生指导,并进行龈上洁治、抛光;观察组在对照组治疗基础上增加龈下刮治和根面平整,2周内每天给予0.2%复方氯己定漱口液漱口。结果:牙周指标方面,对照组术后2、6个月仅有探诊出血情况较治疗前有所降低(P<0.05~P<0.01);而观察组术后2、6个月的探诊出血情况、探诊深度和临床附着距离均较治疗前明显降低(P<0.01)。血脂水平方面,对照组术后2和6个月总胆固醇、三酰甘油、高密度脂蛋白胆固醇、低密度脂蛋白胆固醇4项血脂水平与治疗前差异均无统计学意义(P>0.05),观察组术后2和6个月三酰甘油较治疗前下降(P<0.01),高密度脂蛋白胆固醇上升(P<0.05~P<0.01)。结论:牙周炎的治疗能有效降低三酰甘油脂蛋白水平,提高高密度脂蛋白水平,对改善高血脂症状有明显疗效,值得在临床中推广。

Objective: To study the change of serum lipid level in patients with chronic periodontitis complicated with high blood lipid after treatment. Methods: Sixty-five patients with chronic periodontitis complicated with high blood lipid were divided into the observation group( 32 cases) and control group( 33 cases). The control group was treated with oral hygiene guidance combined with scaling and polishing gum,and the observation group was treated with scaling root surface,flattening root,and rinsing the mouth with 0. 2% compound Gargle solution daily within 2 weeks based on the control group. Results: Compared with before operation,the bleeding at probing technique in control group after 2 and 6 months of operation decreased( P < 0. 05 to P < 0. 01),and the bleeding and depth of probing technique,and clinical adhesion distance significantly decreased in observation group after 2 and 6 months of operation( P <0. 01). The levels of total cholesterol,triglyceride,high density lipoprotein and low density cholesterol in control group between before operation and after 2 and 6 months of operation were not statistically significant( P > 0. 05). Compared with before operation,the levels of triglyceride and high density lipoprotein in observation group decreased and increased after 2 and 6 months of operation,respectively( P < 0. 05 to P < 0. 01). Conclusions: The treatment of periodontitis can effectively reduce the level of triglyceride,increase the level of high density lipoprotein,and improve the symptoms of high blood lipid,which is worthy of popularization in clinic.