梅毒妊娠孕妇死胎的影响因素分析

Analysis of univariate and multivariate stillbirth factors of syphilis pregnant women

目的:分析梅毒妊娠孕妇死胎原因及影响单因素、多因素分析。方法:选取2012年1月至2016年12月98例梅毒孕妇进行前瞻性研究,收集梅毒孕妇的病历资料以及妊娠结局,对其中9例梅毒死胎孕妇和89例正常妊娠梅毒孕妇进行对照观察,就梅毒妊娠孕妇死胎原因进行单因素和多因素分析。结果:婚姻状况、文化程度、吸毒史、TRUST滴度、性伴侣数、是否完成治疗等因素与梅毒孕妇死胎有关,多因素分析结果证实了梅毒孕妇的婚姻状况、TRUST滴度以及是否完成治疗是造成梅毒妊娠孕妇死胎的高危因素。结论:梅毒孕妇TRUST滴度>1∶8以及未完成临床治疗是造成梅毒妊娠孕妇死胎的主要原因。

Objectives： To analyze the causes of stillbirth of syphilis pregnant women and the influence of univariate and multivariate factors. Methods： A prospective study was conducted among 98 pregnant women with syphilis from January 2012 to December 2016. The data of 9 cases of stillbirth and 89 cases of normal pregnancy were analyzed. The univariate and multivariate analysis were done on the influence factors. Results： The marital status,educational level,history of drug use,TRUST titer,sexual partners,and unfinished clinical treatment were related to the stillbirth. Multivariate analysis confirmed the marital status of pregnant women with syphilis,TRUST titer and unfinished clinical treatment were risk factors. Conclusion： TRUST titers〉 1： 8 and unfinished clinical treatment are the main causes of stillbirth in pregnant women with syphilis.