期刊文献+

胰腺神经内分泌肿瘤中MGMT的研究进展 被引量:2

下载PDF
导出
摘要 O6-甲基鸟嘌呤-DNA甲基转移酶(O6-methylguanineDNA-methyltransferse,MGMT)是普遍存在的DNA修复酶,与多种肿瘤的发生、发展密切相关。近年来,MGMT在胰腺神经内分泌肿瘤(pancreatic neuroendocrine neoplasms,pNENs)的预后判断和个性化治疗中的作用备受关注。该文将对MGMT的生物学特性、与pNENs的关系,以及对其状态的不同检测方法在pNENs中的应用价值等方面的研究进展作一综述。
出处 《临床与实验病理学杂志》 CAS CSCD 北大核心 2018年第2期194-197,共4页 Chinese Journal of Clinical and Experimental Pathology
基金 国家基础科学人才培养基金(J1030831/J0108)
  • 相关文献

参考文献2

二级参考文献125

  • 1岳欣,顾锋,夏维波,萧新华,李梅,邢小平,曾正陪,向红丁,连小兰,伍学焱.胰岛素瘤的术前定性及定位诊断99例分析[J].中国实用内科杂志:临床前沿版,2006,26(11):1795-1797. 被引量:16
  • 2Modlin IM, Kidd M, Pfragner R, et al. The functional character- ization of normal and neoplastic human enterochromaffin cells [J]. J C/in Endocrinol Metab,2006, 91 (6) :2340-2348.
  • 3Yao JC, Hassan M, Phan A, et al. One hundred years after "caz'cinoid" : epidemiology of and prognostic factors for neuroen- docrine tumors in 35,825 cases in the United States[ J]. J Clin Oneo1.2008.26 ( 18 ) :3063 - 3072.
  • 4Modlin IM, Lye KD, Kidd M. A 5-decade analysis of 13,715 carcinoid tumors [ J ]. Cancer,2003,97 (4) :934 - 959.
  • 5ho T, Sasano H, Tanaka M, et al. Epidemiological study of gas- troenteropancreatic neuroendocrine tumors in Japan [ J ]. J Gas- troentero1,2010,45 ( 2 ) : 234 - 243.
  • 6Wang YH, Lin Y, Xae L, et al. Relationship between clinical characteristics and survival of gastroenteropancreatic neuroendo- crine neoplasms: A single-institution analysis (1995-2012) in South China[ J] BMC Endocr Disord,2012 ,12 :30.
  • 7Oberg KE. Gastrointestinal neuroendocrine tumors[ J]. Ann On- col ,2010,21 ( Suppl 7 ) : vii 72 - vii 80.
  • 8Jensen RT, Niederle B, Mitry E, et al. Gastrinoma (duodenal and pancreatic ) [ J ]. Neuroendocrinology, 2006,84 ( 3 ) : 173 - 182.
  • 9Krenning EP, Kwekkeboom DJ, Bakker WH, et al. Somatostatin receptor scintigraphy with [ 1111n-DTPA-1)-Phel -and [ 123I-Tyr3 ]-octreotide: the Rotterdam experience with more than 1, 000 patients[J]. Eur J Nucl Med,1993,20(8) :716 -731.
  • 10Lebtahi R, Cadiot G, Sarda L, et al. Clinical impact of soma- tostatin receptor scintigraphy in the management of patients with neuroendocrine gastroenteropancreatic tumors [ J]. J Nucl Med, 1997,38 (6) :853 - 858.

共引文献102

同被引文献16

引证文献2

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部