从“风痰瘀毒”论治三阴性乳腺癌

Treatment of Three Negative Breast Cancer From “Wind Phlegm and Stasis Toxin”

三阴性乳腺癌是一种特殊的乳腺癌亚型,其不适用于内分泌治疗和靶向治疗且易复发转移,因此是当前乳腺癌领域的热点和难点问题。故根据其临床特性提出"脾肾两虚"是三阴性乳腺癌的发病基础,因虚生痰致瘀化风,在虚、痰、瘀的基础上"六淫七情"诱发癌毒,终成"痰毒瘀结"之态。"痰毒"是术后复发转移的主要病理因素,而"内风"是复发转移的推动力量,基于此临证治以"健脾益肾、化痰解毒、活血息风"。从"风痰瘀毒"论治三阴性乳腺癌,是中医药治疗特殊类型乳腺癌的初步探讨,对预防其术后复发转移有一定的指导意义。

Triple negative breast cancer is a special kind of breast cancer subtypes,it does not apply to endocrine therapy and targeted therapy,relapse and metastasis easily. It is the hot spot and difficult problem in the field of breast cancer at present. According to its clinical characteristics. The article puts forward＂spleen and kidney deficiency＂is the pathogenesis basis of triple negative breast cancer,and the Endogenous wind,the Phlegm,the Blood stasis come from the deficiency. Base on these,the＂six climatic exopathogens and seven emotions＂induces the poison,＂stagnation of phlegm,poison and blood stasis＂is the ultimate form. The＂phlegm poison＂is the main pathological factors result in recurrence and metastasis after operation, the＂endogenous wind ＂is the main driving force of recurrence and metastasis,＂spleen invigorating and kidney nourishing,eliminate phlegm and detoxify,invigorate the circulation of blood and calm endogenous wind＂is the main therapeutic principle of triple negative breast cancer. The treatment of triple negative breast cancer based on＂Endogenous wind,Phlegm,Blood stasis and Poison＂,is the preliminary discussion of the special kind of breast cancer subtypes by traditional Chinese medicine therapy,it has some clinical application value.